Ahụ ike ịmụ nwa na-agafe usoro ndụ anyị kpamkpam, bụ nke WHO weere dị ka otu n'ime ihe dị mkpa na-egosi ahụike mmadụ site n'aka WHO.Ka ọ dị ugbu a, "ahụike ọmụmụ maka mmadụ niile" ghọtara dị ka ebumnuche mmepe nke UN Sustainable.Dị ka akụkụ dị mkpa nke ahụike ịmụ nwa, ịrụ ọrụ nke usoro ọmụmụ, usoro na ọrụ dị mkpa maka nwoke ọ bụla.
01 Ihe egwuofọrịa ọmụmụ
Ọrịa na-efe efe nke ịmụ nwa bụ nnukwu ihe iyi egwu na ahụike ọmụmụ nwoke, na-akpata enweghị ọmụmụ n'ihe dịka 15% nke ndị ọrịa.Ihe kpatara ya bụ Chlamydia Trachomatis, Mycoplasma Genitalium na Ureaplasma Urealyticum.Otú ọ dị, ihe dị ka 50% nke ndị ikom na 90% nke ndị inyom nwere ọrịa traktị ọmụmụ bụ subclinical ma ọ bụ asymptomatic, na-eduga na mgbochi na ịchịkwa maka nnyefe nke pathogens na-eleghara anya.Nchọpụta ọrịa ndị a n'oge na nke dị irè na-enyere aka n'ọnọdụ ahụike ọmụmụ dị mma.
Chlamydia Trachomatis ọrịa (CT)
Chlamydia trachomatis urogenital tract ọrịa nwere ike ịkpata urethritis, epididymitis, prostatitis, proctitis na-amụghị nwa na ụmụ nwoke na ọ pụkwara ịkpata cervicitis, urethritis, pelvic mkpali ọrịa, adnexitis, na-amụghị nwa na ụmụ nwanyị.N'otu oge ahụ, ọrịa Chlamydia trachomatis n'ime ụmụ nwanyị dị ime nwere ike iduga mgbawa akpụkpọ ahụ n'oge akaghi aka, ịmụ nwa, ite ime n'onwe ya, endometritis mgbe imechara ime na ihe ndị ọzọ.Ọ bụrụ na a naghị agwọta ya nke ọma n'ime ụmụ nwanyị dị ime, enwere ike ibunye ya ozugbo nye ụmụ amụrụ ọhụrụ, na-ebute ophthalmia, nasopharyngitis na oyi baa.Ọrịa genitourinary na-adịghị ala ala yana ugboro ugboro na-efe efe Chlamydia trachomatis na-etolite na-ebute ọrịa, dị ka cervical squamous cell carcinoma na AIDS.
Ọrịa Neisseria Gonorrheae (NG)
Ngosipụta ụlọ ọgwụ nke Neisseria gonorrheae urogenital tract ọrịa bụ urethritis na cervicitis, na ihe mgbaàmà ya bụ dysuria, urination ugboro ugboro, ngwa ngwa, dysuria, imi ma ọ bụ purulent purulent.Ọ bụrụ na a naghị agwọ ya n'oge, gonococci nwere ike ịbanye na urethra ma ọ bụ gbasaa site na cervix, na-akpata prostatitis, vesiculitis, epididymitis, endometritis, na salpingitis.N'ọnọdụ ndị siri ike, ọ nwere ike ibute gonococcal sepsis site na mgbasa nke hematogenous.Mucosal necrosis nke na-akpata squamous epithelium ma ọ bụ ihe jikọrọ anụ ahụ nwere ike iduga na urethra siri ike, vas deferens na tubal narrowing ma ọ bụ ọbụna atresia na ọbụna ime ectopic na-amụghị nwa na ma nwoke ma nwanyị.
Ọrịa Ureaplasma Urealyticum (UU)
Ureaplasma urealyticum na-abụkarị parasitic na urethra nwoke, apị nke amụ, na ikpu nwanyị.Ọ nwere ike ibute ọrịa urinary tract na enweghị ọmụmụ n'okpuru ọnọdụ ụfọdụ.Ọrịa ureaplasma na-ebutekarị bụ nongonococcal urethritis, nke na-akpata 60% nke urethritis na-abụghị nje.Ọ nwekwara ike ịkpata prostatitis ma ọ bụ epididymitis na ụmụ nwoke, vaginitis na ụmụ nwanyị, cervicitis, ọmụmụ akaghi aka, ịdị arọ nwa dị ala, ma nwee ike ibute ọrịa nke akụkụ iku ume na usoro ụjọ nke etiti nke ụmụ amụrụ ọhụrụ.
Ọrịa nje virus Herpes Simplex (HSV)
A na-ekewa nje virus Herpes simplex ụzọ abụọ: ọrịa herpes simplex ụdị 1 na ụdị nje virus nke 2. Herpes simplex virus ụdị 1 na-ebute herpes ọnụ na-abụkarị site n'ọnụ na ọnụ, ma ọ pụkwara ịkpata herpes genital.Herpes simplex virus ụdị 2 bụ ọrịa a na-ebute site ná mmekọahụ nke na-ebute herpes genital.Herpes Genital nwere ike ịmaliteghachi ma nwee mmetụta dị ukwuu na ahụike na akparamàgwà ndị ọrịa.O nwekwara ike ibunye ụmụ amụrụ ọhụrụ site na placenta na ọwara ọmụmụ, na-ebute ọrịa nke ụmụ amụrụ ọhụrụ na-ebute.
Ọrịa Mycoplasma Genitalium (MG)
Mycoplasma genitalium bụ obere genome organism nke na-emegharị onwe ya na naanị 580kb ma bụrụkwa nke a na-ahụ ya n'ime mmadụ na anụ ụlọ.N'ime ndị na-eto eto na-enwe mmekọahụ, enwere mmekọrịta siri ike n'etiti urogenital tract abnormalities na Mycoplasma genitalium, ebe ihe ruru 12% nke ndị ọrịa na-egosi mgbaàmà na-adị mma maka Mycoplasma genitalium.Na mgbakwunye, pepole butere Mycoplasma Genitalium nwekwara ike ịmalite na-abụghị gonococcal urethritis na prostatitis na-adịghị ala ala.Mycoplasma genitalium ọrịa bụ ihe na-akpata onwe ya na-akpata mbufụt nke cervical maka ụmụ nwanyị na-ejikọta ya na endometritis.
Ọrịa Mycoplasma Hominis (MH)
Mycoplasma hominis ọrịa nke genitourinary tract nwere ike ịkpata ọrịa ndị dị ka urethritis na-abụghị gonococcal na epididymitis na ụmụ nwoke.Ọ na-egosipụta dị ka mbufụt nke usoro ọmụmụ na ụmụ nwanyị na-agbasa na-adabere na cervix, na ihe na-emekarị bụ salpingitis.Endometritis na ọrịa pelvic inflammatory nwere ike ime na ọnụ ọgụgụ dị nta nke ndị ọrịa.
02Ngwọta
Macro & Micro-Test etinyela aka na mmepe nke ọrịa na-ahụ maka ọrịa urogenital tract, wee mepụta ngwa nchọpụta metụtara (usoro nchọpụta Isothermal Amplification) dị ka ndị a:
03 Nkọwapụta ngwaahịa
| Aha ngwaahịa | Nkọwapụta |
| Chlamydia Trachomatis Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 ule/kit 50 ule/kit |
| Ngwa Neisseria Gonorrheae Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 ule/kit 50 ule/kit |
| Ureaplasma Urealyticum Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 ule/kit 50 ule/kit |
| Ụdị nje virus nke Herpes Simplex 2 Ngwa nchọpụta Nucleic Acid (Enzymatic Probe Isothermal Amplification) | 20 ule/kit 50 ule/kit |
04 Auru
1. A na-ewebata njikwa ime n'ime usoro a, nke nwere ike nyochaa usoro nyocha nke ọma ma hụ na ọ dị mma.
2. Usoro nchọpụta Isothermal Amplification bụ obere oge ule, na nsonaazụ nwere ike nweta n'ime nkeji 30.
3. Na Macro & Micro-Test Sample Release Reagent na Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006), ọ dị mfe iji rụọ ọrụ ma dabara maka ọnọdụ dị iche iche.
4. Mmetụta dị elu: LoD nke CT bụ 400copy / mL;LoD nke NG bụ 50 pcs / ml;LoD nke UU bụ 400copy/mL;LoD nke HSV2 bụ 400 mbipụta / ml.
5. Elu nkọwa: enweghị cross-reactivity na ndị ọzọ metụtara na-efe efe (dị ka syphilis, genital warts, chancroid chancre, trichomoniasis, ịba ọcha n'anya B na AIDS).
Ntụaka:
[1] LOTTI F,MAGGI M. Mmekọahụ arụrụ arụ na enweghị ọmụmụ nwoke [J].NatRev Urol,2018,15(5):287-307.
[2] CHOY JT,EISENBERG ML.Amụghị nwoke dị ka windo ahụike[J].Fertil Steril,2018,110(5):810-814.
[3] ZHOU Z,ZHENG D,WU H,et al.Epidemiology of infertility in China:apopulation based study[J].BJOG,2018,125(4):432-441.
Oge nzipu: Nov-04-2022