Mycobacterium ụkwara nta Nucleic Acid na Rifampicin Nguzogide

Mycobacterium ụkwara nta, obere oge dị ka Tubercle bacillus, TB, bụ nje nje na-akpata ụkwara nta.Ugbu a, ọgwụ mgbochi ụkwara nta nke mbụ a na-ejikarị gụnyere isoniazid, rifampicin na hexambutol, wdg. Ọgwụ mgbochi ụkwara nta nke abụọ gụnyere fluoroquinolones, amikacin na kanamycin, wdg. Ọgwụ ọhụrụ emepụtara bụ linezolid, bedaquiline na delamani, wdg. Otú ọ dị, n'ihi iji ọgwụ mgbochi ụkwara nta na-ezighị ezi na njirimara nke mgbidi cell nke ụkwara nta nke mycobacterium, ụkwara nta mycobacterium na-emepụta ọgwụ na-eguzogide ọgwụ mgbochi ụkwara nta, nke na-eweta nnukwu nsogbu na mgbochi na ọgwụgwọ ụkwara nta.

A na-eji Rifampicin na-agwọ ndị ọrịa ụkwara nta nke akpa ume kemgbe afọ 1970, ma nwee mmetụta dị ukwuu.Ọ bụ nhọrọ mbụ iji belata ọgwụgwọ ọgwụgwọ nke ndị ọrịa ụkwara nta.Ihe na-akpata nguzogide Rifampicin bụ ngbanwe nke mkpụrụ ndụ ihe nketa rpoB.Ọ bụ ezie na ọgwụ ọhụrụ na-egbochi ụkwara nta na-apụta mgbe nile, na ịdị irè ụlọ ọgwụ nke ndị ọrịa ụkwara nta na-aga n'ihu na-agakwa n'ihu, a ka nwere ụkọ ọgwụ mgbochi ụkwara nta, na ọdịdị nke iji ọgwụ na-enweghị isi eme ihe na ụlọ ọgwụ dị oke elu.N'ụzọ doro anya, ọrịa ụkwara nta nke Mycobacterium nke ndị ọrịa nwere ụkwara nta akpa ume enweghị ike igbu kpamkpam n'oge kwesịrị ekwesị, nke na-emecha na-eduga n'ọkwa dị iche iche nke nguzogide ọgwụ n'ime ahụ onye ọrịa, na-agbatị usoro nke ọrịa ahụ, na-abawanye ohere nke ọnwụ nke onye ọrịa.