Ụdị 18 nke Nje Virus Nucleic Acid Papilloma nke mmadụ nwere nnukwu ihe ize ndụ

Ụdị 18 dị oke egwu mmadụ papilloma Virus Nucleic Acid egosipụtara onyogho

Nkọwa dị mkpirikpi:

Ngwa a dabara adaba maka nchọpụta qualitative in vitro nke ụdị nje papilloma mmadụ 18 (HPV) (HPV16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) Iberibe nucleic acid dị na ụmụ nwoke / mmamịrị nwanyị na mkpụrụ ndụ exfoliated nwanyị na mkpụrụ ndụ HPV 16/18.

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Aha ngwaahịa

Ụdị HWTS-CC011A-18 nke Ngwa Papilloma Virus Nucleic Acid Detection Kit (Fluorescence PCR) dị ize ndụ

Asambodo

Epidemiology

Ọrịa kansa cervical bụ otu n'ime etuto ọjọọ na-adịkarị na traktị ọmụmụ ụmụ nwanyị.Nnyocha e mere egosiwo na ọrịa na-adịgide adịgide na ọtụtụ ọrịa papillomavirus mmadụ bụ otu n'ime ihe ndị dị mkpa na-ebute ọrịa kansa cervical.

Ọrịa HPV na-amụ nwa bụ ihe a na-ahụkarị n'etiti ụmụ nwanyị nwere ndụ mmekọahụ.Dị ka ọnụ ọgụgụ si kwuo, pasent 70 ruo 80 nke ụmụ nwanyị nwere ike ịrịa ọrịa HPV otu ugboro ma ọ dịkarịa ala n'oge ndụ ha, mana ọtụtụ ọrịa na-ebute onwe ha, ihe karịrị 90% nke ndị inyom bu ọrịa ga-emepụta nzaghachi dị mma nke na-adịghị ahụkebe nke nwere ike ikpochapụ ọrịa ahụ. n'etiti ọnwa 6 na 24 na-enweghị enyemaka ahụike ogologo oge.Ọrịa HPV nwere nnukwu ihe ize ndụ na-adịgide adịgide bụ isi ihe kpatara neoplasia intraepithelial cervical na ọrịa kansa cervical.

Nsonaazụ ọmụmụ ihe zuru ụwa ọnụ gosiri na ahụrụ ọnụnọ nke HPV DNA dị ize ndụ na 99.7% nke ndị ọrịa cancer cervical.Ya mere, nchọpụta mmalite na mgbochi nke HPV cervical bụ isi ihe na-egbochi ọrịa cancer.Ịmepụta usoro nchọpụta ọrịa dị mfe, kpọmkwem na ngwa ngwa dị oke mkpa na nchọpụta ụlọ ọgwụ nke ọrịa cancer cervical.

Ọwa

FAM	HPV 18
VIC (HEX)	HPV 16
ROX	HPV 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82
CY5	Njikwa ime

Nka nka

Nchekwa	≤-18℃ n'ọchịchịrị
Ndụ nchekwa	Ọnwa iri na abụọ
Ụdị ụdị	Selụ exfoliated cervical
Ct	≤28
CV	≤5.0％
LoD	300 oyiri/ml
Nkọwapụta	Ọ dịghị cross-reactivity na nkịtị ọmụmụ tract pathogens (dị ka ureaplasma urealyticum, genital tract chlamydia trachomatis, candida albicans, neisseria gonorrhoeae, trichomonas vaginalis, ebu, gardnerella na ndị ọzọ HPV ụdị adịghị ekpuchi na kit, wdg).
Ngwa ndị ọdabara	Ọ nwere ike dabara na ngwa PCR fluorescent nke dị n'ahịa. Sistemụ PCR SLAN-96P ezigbo oge Sistemụ PCR ABI 7500 ezigbo oge Sistemụ PCR Real-Time QuantStudio®5 LightCycler®480 PCR ozugbo Sistemụ nchọpụta PCR nke LineGene 9600 Plus MA-6000 Real-Time Quantitative Thermal Cycler